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Preclinical R&D Expert – In-house Drug Development

Company: Mercor · Pay: $60–$100/hr · Location: Remote — Global · Type: contractor, part time · Posted: 2026-09-14

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$60 - $100 / hr

The Convergence of Artificial Intelligence and In-House Preclinical Drug Discovery

The pharmaceutical industry stands at the precipice of a monumental paradigm shift. For decades, traditional drug discovery has been an agonizingly slow, high-attrition process requiring billions of dollars and countless hours in the wet lab to bring a single candidate from initial target identification through lead optimization, IND-enabling studies, and finally into clinical trials. While traditional discovery methods have served science well, the sheer biological and chemical complexity of modern therapeutics demands a radically accelerated approach.

Enter artificial intelligence and physics-based foundation models. Venture-backed AI labs are currently building frontier computing platforms designed specifically for chemistry, materials science, and macromolecular modeling. However, these advanced algorithms cannot train themselves in a vacuum. They require authentic, highly nuanced wet-lab expertise from seasoned preclinical R&D scientists who have actually guided molecules and biological assets from the bench toward the clinic. Platforms like Mercor are bridging this gap, offering elite biotech professionals a lucrative avenue to monetize their hard-earned translational experience through high-paying remote advisory and evaluation roles.

Detailed Job Description: What the Preclinical R&D Expert Role Entails

This unique remote engagement invites hands-on drug discovery scientists to act as core guides for cutting-edge AI labs developing physics-based models. If you have spent your career optimizing molecular structures, evaluating pharmacokinetic-pharmacodynamic (PK-PD) profiles, or managing complex preclinical pipelines, your insights will directly dictate how intelligent systems reason about pharmaceutical R&D.

Core Responsibilities:

  • Technical Review & Data Evaluation: Assess intricate technical materials, real-world R&D datasets, and model outputs within your specific domain of pharmaceutical expertise.
  • Scientific Annotation & Labeling: Label, classify, and annotate complex scientific data and computational outputs to dramatically improve foundation model performance and accuracy.
  • Strategic Advisory & Risk Assessment: Provide expert perspective on critical R&D decision points, including target selection, modality optimization, chemical trade-offs, and preclinical risk mitigation.
  • Pipeline Standard Definition: Help structure and refine rigorous quality standards for the client's proprietary scientific dataset pipeline.
  • Expert Collaborations: Engage directly with client research teams through structured interviews, technical discussions, and collaborative research engagements.

Candidate Qualifications and Requirements

Because these frontier models are utilized by leading life sciences enterprises, the qualification bar is intentionally established for active practitioners rather than academic theorists or generalized consultants.

Must-Have Qualifications:
  • In-House Discovery Experience: Hands-on, non-administrative preclinical R&D experience at a biotechnology company that develops its own proprietary drug assets and has actively taken programs toward the clinic.
  • Core R&D Functionality: Professional background rooted in a core R&D discipline: discovery biology, medicinal chemistry, protein and antibody engineering, computational biology, in vivo/translational science, pharmacology/PK-PD, toxicology, or CMC/formulation.
  • Modality Expertise: Hands-on familiarity with one or more advanced drug modalities, such as small molecules, monoclonal antibodies, peptides, ADCs, bispecifics, mRNA, siRNA, ASOs, PROTACs, molecular glues, cell therapies, gene therapies, or radioligand therapies.
  • Experience Threshold: 5+ years of relevant industry R&D experience (adaptable based on depth and impact of portfolio).

Important Note on Scope: This role is specifically tailored for in-house therapeutics developers. It is generally not the right fit for professionals whose primary background is restricted to CRO/CDMO services, pure academia, quality control/analytical testing only, clinical-stage development only, diagnostics, or regulatory/medical writing.

Contract Terms, Flexibility, and Financial Rewards

Designed for busy biotechnology professionals who want to maintain their primary commitments or enjoy consulting freedom, Mercor contracts offer unmatched scheduling autonomy:

  • Independent Contractor Status: Operate flexibly on an ongoing, part-time engagement averaging roughly 10 hours per week, completed entirely on your own schedule.
  • Direct Client Interface: Work hand-in-hand directly with innovative client research teams from individual contributor levels up through Director.
  • Reliable Global Compensation: Enjoy competitive hourly pay ranging from $60 to $100 per hour, disbursed weekly via global payment networks like Stripe and Wise. Note that H1-B or STEM OPT support is currently unavailable for this track.

Why Preclinical Experts Are Pivoting to AI Training

Traditional biotechnology career tracks often lock scientists into rigid laboratory hours, heavy administrative burdens, or corporate silos. By participating in AI model training through Mercor, researchers can step into the tech-bio revolution without leaving their core areas of passion. You are not just consulting; you are actively shaping the analytical tools that will empower the next generation of life-saving medicines.

Furthermore, this engagement provides a fantastic financial upside while keeping your intellectual curiosity sharp. By dedicating roughly 10 hours a week to evaluating physics-based AI models, you position yourself at the vanguard of computational biology and drug discovery innovation.

Secure Your Role in the Future of Drug Discovery

Opportunities to influence foundational artificial intelligence models in the pharmaceutical space are exceptionally rare and highly sought after by top-tier scientists. If your background matches the rigorous preclinical and modality requirements outlined above, take the next step today.

Responsibilities

  • Technical Review & Data Evaluation: Assess intricate technical materials, real-world R&D datasets, and model outputs within your specific domain of pharmaceutical expertise.
  • Scientific Annotation & Labeling: Label, classify, and annotate complex scientific data and computational outputs to dramatically improve foundation model performance and accuracy.
  • Strategic Advisory & Risk Assessment: Provide expert perspective on critical R&D decision points, including target selection, modality optimization, chemical trade-offs, and preclinical risk mitigation.
  • Pipeline Standard Definition: Help structure and refine rigorous quality standards for the client's proprietary scientific dataset pipeline.
  • Expert Collaborations: Engage directly with client research teams through structured interviews, technical discussions, and collaborative research engagements.

Qualifications

  • In-House Discovery Experience: Hands-on, non-administrative preclinical R&D experience at a biotechnology company that develops its own proprietary drug assets and has actively taken programs toward the clinic.
  • Core R&D Functionality: Professional background rooted in a core R&D discipline: discovery biology, medicinal chemistry, protein and antibody engineering, computational biology, in vivo/translational science, pharmacology/PK-PD, toxicology, or CMC/formulation.
  • Modality Expertise: Hands-on familiarity with one or more advanced drug modalities, such as small molecules, monoclonal antibodies, peptides, ADCs, bispecifics, mRNA, siRNA, ASOs, PROTACs, molecular glues, cell therapies, gene therapies, or radioligand therapies.
  • Experience Threshold: 5+ years of relevant industry R&D experience (adaptable based on depth and impact of portfolio).

Apply now →